Question
In the context of hereditary diseases, consider the following statements
1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg.
2. A child inherits mitochondrial diseases entirely from mother and not from father.
Which of the statements given above is/are correct?
(a) 1 only
(b) 2 only
(c) Both 1 and 2
(d) Neither 1 nor2
Answer:
C
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Explanation:
Statement 1 is correct: Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy, which involves replacing the defective mitochondria with healthy ones through in vitro fertilization techniques.
Statement 2 is also correct: Mitochondrial DNA is primarily inherited from the mother, as sperm cells typically do not contribute mitochondria to the embryo during fertilization. Therefore, mitochondrial diseases are usually inherited maternally.